The star-studded team, without injured player Neymar, saw Lionel Messi and Kylian Mbappe join forces to lead their team to victory.
Mbappe scored two goals and became PSG's joint record scorer with Edinson Cavani, while Messi netted his 700th goal in club football.
Marseille coach Igor Tudor expressed no regret over his team's high-risk approach, but PSG centre-back Sergio Ramos praised his team's aggression and intensity.
"We were aggressive, we put intensity into the game, that's what we'd been missing," said Ramos.
PSG suffered an early injury blow when Presnel Kimpembe left the pitch on a stretcher, but they were focused throughout at the Velodrome. Matteo Guendouzi created danger as Marseille pressed high and hard, but they were exposed on the counter, and the hosts were punished in the 25th minute when Messi played Mbappe through for France forward to race into the area and beat Pau Lopez with a low shot.
The roles were reversed four minutes later as Mbappe delivered a pin-point cross for Messi, who tapped in from point-blank range to double the advantage in front of an all-time Ligue 1 record attendance of 65,800.
Messi then missed a sitter and Mbappe was denied by Lopez after being found in the area by the Argentine again, just before Marquinhos's angled shot went just wide as Marseille were again caught on the break. Messi beautifully lifted the ball into the path of Mbappe, who volleyed home with his left foot for his 16th goal of the season in Ligue 1.
Gianluigi Donnarumma made a spectacular save from Nuno Tavares's header in the 67th to snuff out any hope of a Marseille comeback as PSG secured its first clean sheet in six league games.
Third-placed Monaco slumped to a 3-0 home defeat against Nice, who prevailed thanks to a Terem Moffi double and a superb half-volley by Khephren Thuram. The result left Monaco on 50 points, ahead of fourth-placed RC Lens on goals scored after the northerners drew 1-1 at Montpellier on Saturday.
PSG's next match is at home against Nantes before they travel to Bayern Munich for their Champions League last-16 return leg.