The Polish player rose to No. 1 after a sudden retirement by Ashleigh Barty and has since been unstoppable in any Grand Slam she participated in.
Swiatek swept past Alison Riske of the United States 6-0, 6-2 to reach the third round as only three of the top 10 women's seeds survived the opening two rounds.
Eighth-seeded Karolina Pliskova and Danielle Collins, the ninth seed, joined fellow top 10 players, defending champion Barbora Krejcikova, Maria Sakkari, Ons Jabeur, Anett Kontaveit and former winner Garbine Muguruza in failing to reach the last 32.
Swiatek, the 2020 champion in Paris, is on the best streak since Serena Williams's 34-match winning run in 2013 and goes on to face Danka Kovinic of Montenegro for a place in the last 16.
Swiatek raced through the first set against 43rd-ranked Riske in just 21 minutes and was 3-0 up in the second before the American avoided a 'double bagel'.
The Pole still managed to take her record of 6-0 sets in 2022 to a season-leading 15.
"I'm pretty happy to play some solid tennis," said Swiatek who joins third seed Paula Badosa and seventh-seeded Aryna Sabalenka in the last 32.